Find the best doctors for treating Esophageal Cancer in Miami. Our team approach is particularly important in esophageal cancer, which is often best managed using a combination of chemotherapy, radiation therapy, and surgery. What treatments you receive for esophageal cancer are based on the type of cells involved in your cancer, your cancer's stage, your overall health and your preferences for treatment. Burmeister BH, Smithers BM, Gebski V, et al. It’s also important to follow recommended screening guidelines, which can help detect certain cancers early. An endoscopy procedure involves inserting a long, flexible tube (endoscope) down your throat and into your esophagus. This type of recurrence is often treated with surgery to remove the esophagus. If your family doctor suspects you have esophageal cancer, you may be referred to a number of doctors who will help evaluate your condition. These treatments cause minimal esophageal trauma, have a low risk of complications and preserve the esophagus. Tests and procedures used to diagnose esophageal cancer include: Once a diagnosis of esophageal cancer is confirmed, your doctor may recommend additional tests to determine whether your cancer has spread to your lymph nodes or to other areas of your body. Esophageal and gastroesophageal junction (GEJ) cancer (adult). Management of esophageal cancer. A single copy of these materials may be reprinted for noncommercial personal use only. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. Posner MC, Goodman KA, and Ilson DH. Research. Esophageal cancer and its treatment can also cause the esophagus to narrow and/or become dry, sore, and irritated, … We offer the most advanced treatments available today -- from radiation and chemotherapy to esophagectomy, including minimally invasive and robotic surgery options. For reprint requests, please see our Content Usage Policy. Elsevier; 2020. https://www.clinicalkey.com. The American Cancer Society is a qualified 501(c)(3) tax-exempt organization. Other treatment options for local recurrence after surgery might include more surgery or other treatments to help prevent or relieve symptoms. Esophageal and esophagogastric junction cancers. Your options depend on which, if any, drugs you received before the cancer came back and how long ago you received them, as well as on your health. For metastatic or recurrent gastroesophageal cancer that is HER2 positive, ASCO, ASCP, and CAP recommend a combination of chemotherapy and HER2-targeted therapy . Jan. 21, 2020. Stage III includes some cancers that have grown through the wall of the esophagus to the outer layer, as well as cancers that have grown into nearby organs or tissues. Our radiation oncologists use state-of-the-art equipment and the latest imaging techniques, and are assisted by experienced and expert staff. © 1998-2021 Mayo Foundation for Medical Education and Research (MFMER). Esophageal cancer. The American Cancer Society couldn’t do what we do without the support of our partners. Surgery alone is typically used only in patients with early-stage disease, according to Shah. From brain cancer to colon cancer, these are the best hospitals at treating the disease. Some people prefer not to have treatments that have serious side effects and choose to receive only treatments that will help keep them comfortable and add to their quality of life. https://www.uptodate.com/contents/search. Surgery for Esophageal Cancer. Can you explain the pathology report to me? J Clin Oncol. In addition to offering state of the art diagnostic techniques and esophageal cancer treatment methods, our specialists offer an array of resources that can help patients cope with the demands of cancer. Radiation therapy is also used to relieve complications of advanced esophageal cancer, such as when a tumor grows large enough to stop food from passing to your stomach. The type of treatment(s) your doctor recommends will depend on the stage of the cancer and on your overall health. Get personalized treatment. CA Cancer J Clin. Become a volunteer, make a tax-deductible donation, or participate in a fundraising event to help us save lives. Photodynamic therapy: After a light-activated drug is injected into your vein, it settles in cancer … Stage II/III (Intermediate stage): The best treatment option for intermediate stage esophageal cancer is to shrink tumors through a combination of six weeks of chemotherapy and radiation followed by surgical removal. If chemotherapy was given before, it is usually still possible to give more chemotherapy. Sometimes the same drugs that were used before are given again, but often other drugs are used. Accessed Dec. 26, 2019. When the cancer is only in the esophagus itself and perhaps some nearby lymph nodes, we typically combine different types of treatments to get the best results. They have not grown into deeper layers of the esophagus. This experience means that we can provide you with the most advanced, effective radiation treatment possible. The remaining esophagus is reconnected to your stomach. All rights reserved. [PMID: 26389338]. View Patient Education and Support resources However, with any surgery, there is always the possibility of complications, such as infection, bleeding, numbness, swelling and scar tissue. 2013;63:232–248. American Society of Clinical Oncology. Moffitt is a high-volume cancer center, and we regularly treat patients with uncommon and complex malignancies such as esophageal cancer. Cancer of the esophagus. One operation used to treat esophageal cancer is esophagectomy. Close follow-up with endoscopy is very important in looking for possible signs of cancer returning. At Treatment Possible, our main objective is to provide the best options in India for your treatment of Esophageal cancer at the lowest cost. Stage IV esophageal cancer has spread to distant lymph nodes or to other distant organs. Treatments for esophageal obstruction and difficulty swallowing (dysphagia) can include: Chemotherapy is drug treatment that uses chemicals to kill cancer cells. Accessed at www.nccn.org/professionals/physician_gls/pdf/esophageal.pdf on Jan 23, 2020. 2014 Jan 13. Chemotherapy drugs are typically used before (neoadjuvant) or after (adjuvant) surgery in people with esophageal cancer. National Comprehensive Cancer Network (NCCN). Esophageal Cancer Staging and Treatment Options Esophageal Cancer Stages. For people who are healthy enough, treatment for these cancers is most often chemoradiation followed by surgery. Philadelphia, Pa. Elsevier: 2020. For esophageal cancer, targeted drugs are usually combined with chemotherapy for advanced cancers or cancers that don't respond to other treatments. Complementary and alternative therapies may help you cope with the side effects of cancer and cancer treatment. Treatment options that may be used for esophageal cancer include: Surgery is the most common treatment for esophageal cancer. Recurrent cancers can often be hard to treat, so you might also want to ask your doctor if you might be eligible for clinical trials involving newer treatments. Eating with esophageal cancer can present difficulties for patients before, during, and after treatment. NCCN Clinical Practice Guidelines in Oncology: Esophageal and Esophagogastric Junction Cancers. Five types of standard treatment are used: Surgery: Surgery is the most common treatment for cancer of the esophagus. Using a scope to examine your esophagus (endoscopy). For esophageal cancer, immunotherapy might be used when the cancer is advanced, cancer has come back or the cancer has spread to other parts of the body. These treatments are more likely to be useful for earlier stage (less advanced) cancers, although they might also be used in some other situations. Your health care team may include doctors who: To get the most from your appointment, it's a good idea to be well prepared. Options include chemotherapy and surgery ; or a combination of chemotherapy, radiation therapy and surgery. Oesophageal cancer is often treatable. As a cancer treatment, these antibodies can attach to a specific target on cancer cells or other cells that may help cancer cells grow. The abnormal cells look like cancer cells, but they are only found in the inner layer of cells lining the esophagus (the epithelium). From basic information about cancer and its causes to in-depth information on specific cancer types – including risk factors, early detection, diagnosis, and treatment options – you’ll find it here. This is Cancer.Net’s Guide to Esophageal Cancer. 2012;366:2074–2084. Whether you or someone you love has cancer, knowing what to expect can help you cope. Radiation therapy or other treatments may be used to help with pain or trouble swallowing. Patients may go through radiation therapy, chemotherapy, surgery, or any combination of these in an effort to eliminate or beat back the cancer. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. AskMayoExpert. Cameron AM, et al. Elsevier; 2020. https://www.clinicalkey.com. Therapies may include endoscopic mucosal resection, radiofrequency ablation or photodynamic therapy. But combining chemotherapy and radiation treatments increases the likelihood and severity of side effects. 2. PDQ Esophageal Cancer Treatment (Adult). Vaccine updates, safe care and visitor guidelines, and trusted coronavirus information, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, Our caring team of Mayo Clinic experts can help you with your esophageal cancer-related health concerns, FREE book offer – Mayo Clinic Health Letter, New Year Special -  40% off – Mayo Clinic Diet Online. Or, you can choose another section to learn more about a specific question you have. Treatment is used mainly to help keep the cancer under control for as long as possible and to relieve any symptoms it is causing. But most patients with T1 cancers who are healthy enough will have surgery (esophagectomy) to remove the part of their esophagus that contains the cancer. N Engl J Med. No esophageal cancer patient is the same. Radiation therapy is most often combined with chemotherapy in people with esophageal cancer. Surgery alone may be an option for some small tumors. Other times, ablation alone is enough treatment. Patients are encouraged to take advantage of these resources to ease the burden of managing cancer. If the cancer was initially treated endoscopically (such as with endoscopic mucosal resection or photodynamic therapy), it most often comes back in the esophagus. Your doctor uses the information from these procedures to assign a stage to your cancer. If the cancer is in the upper part of the esophagus (in the neck), chemoradiation may be recommended as the main treatment instead of surgery. What websites do you recommend? Our team is made up of doctors and oncology certified nurses with deep knowledge of cancer care as well as journalists, editors, and translators with extensive experience in medical writing. Combined chemotherapy and radiation may be the only treatment you receive, or combined therapy can be used before surgery. A metal tube (stent) can be used to hold open a narrowed portion of the esophagus. The stage of cancer determines how serious the cancer is as well as what the best form of treatment will be. Esophageal cancer is a complex disease that develops when cancer forms in the esophagus, which is the hollow, muscular tube connecting the throat to the stomach. You may feel overwhelmed just when you need to make crucial decisions. Long-term follow-up with frequent upper endoscopy is very important after endoscopic treatment to continue to look for pre-cancer (or cancer) cells in the esophagus. Monoclonal antibody therapy is a type of targeted therapy used in the treatment of esophageal cancer. Over the last few years, several new drugs have increased the options for esophageal cancer. Accessed Dec. 26, 2019. Springer; 2017. Whether you want to learn about treatment options, get advice on coping with side effects, or have questions about health insurance, we’re here to help. Patterns of recurrence after surgery alone versus preoperative chemoradiotherapy and surgery in the CROSS trials. Collecting a sample of tissue for testing (biopsy). The success rate for Esophageal Cancer Treatment in Mexico is now extremely high given the recent advances in medical technology and surgeon experience. You may find strength and encouragement in being with people who are facing the same challenges you are. https://www.cancer.net/cancer-types/esophageal-cancer/view-all. Compare doctors, read patient reviews and more. There are different types of treatment for patients with esophageal cancer. The cancer staging system continues to evolve and is becoming more complex as doctors improve cancer diagnosis and treatment. Ablation for treatment of esophageal cancer is used only in case of in situ cancer when the tumor has not yet sprouted into neighboring tissues. You can help reduce your risk of cancer by making healthy choices like eating right, staying active and not smoking. Long-term follow-up with frequent upper endoscopy is very important after endoscopic treatment to continue to look for pre-cancer (or cancer) cells in the esophagus. Chemotherapy can also be combined with radiation therapy. Mayo Clinic; 2017. Learn more about our expertise in radiation therapy for esophageal cancer. Abeloff’s Clinical Oncology. Cancer Information, Answers, and Hope. We can even find you a free ride to treatment or a free place to stay when treatment is far from home. Or try online message boards, such as those available through the American Cancer Society. Here's some information to help you get ready, and to know what to expect from your doctor. Accessed 01/31/2020. Esophageal cancer that recurs in distant parts of the body is treated like a stage IV cancer. Operations used to treat esophageal cancer include: Esophageal cancer surgery carries a risk of serious complications, such as infection, bleeding and leakage from the area where the remaining esophagus is reattached to the stomach. Unfortunately, even when cancer cannot be seen, it can still be present below the inner lining of the esophagus, so close follow-up is very important. Patients with adenocarcinoma at the place where the stomach and esophagus meet (the gastroesophageal junction) are sometimes treated with chemo (without radiation) followed by surgery. Side effects of radiation to the esophagus include sunburn-like skin reactions, painful or difficult swallowing, and damage to nearby organs, such as the lungs and heart. With time, each person finds a way of coping and coming to terms with the diagnosis. In general, these cancers are very hard to get rid of completely, so surgery to try to cure the cancer is usually not a good option. Making Strides Against Breast Cancer Walks, Common Questions About the COVID-19 Outbreak, Targeted Drug Therapy for Esophageal Cancer, Endoscopic Treatments for Esophageal Cancer. ESOPHAGEAL CANCER TREATMENT. We’ve invested more than $4.9 billion in cancer research since 1946, all to find more – and better – treatments, uncover factors that may cause cancer, and improve cancer patients’ quality of life. In this stage the cancer has grown into some of the deeper layers of the esophagus wall (past the innermost layer of cells) but has not reached the lymph nodes or other organs. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. https://www.uptodate.com/contents/search. Surgery is usually the first line of defense against esophageal cancer. Gibson MK, et al. Tax ID Number: 13-1788491. Esophagus and esophagogastric junction. Another option at some point might be treatment with the immunotherapy drug pembrolizumab (Keytruda) or the chemotherapy combination pill trifluridine–tipiracil (Lonsurf). Chemotherapy is the main treatment for advanced esophageal cancer. Esophageal Cancer People with esophageal cancer travel to Duke from all over the U.S. to benefit from our expertise, comprehensive treatment options, and breakthrough research. Bethesda, MD: National Cancer Institute. By stage IV, the cancer is considered advanced and has spread to other areas of the body. 8th ed. Cancer.org is provided courtesy of the Leo and Gloria Rosen family. How your surgery is performed depends on your individual situation and your surgeon's particular approach to managing it. Endoscopic Treatments for Esophageal Cancer. Dysphagia, for example, may reach a point when a liquid-only diet is necessary. As one of the world's largest cancer research centers, MD Anderson is leading the investigation into new methods of esophageal cancer prevention, diagnosis and treatment. Until you find what brings you the most comfort, consider trying to: Find someone to talk to. Our researchers are constantly striving to learn more about the biology behind esophageal cancer, cancer resistance and cancer … For cancers that started at the gastroesophageal (GE) junction, treatment with the targeted drug ramucirumab (Cyramza) may be an option at some point. Lagergren J, Lagergren P. Recent developments in esophageal adenocarcinoma. Radiation therapy may be an option to relieve symptoms as well. This is also called 0 stage of cancer. Your doctor uses your cancer stage to select the treatments that are right for you. Oppedijk V, van der Gaast A, van Lanschot JJ, et al. Or, less commonly, radiation can be placed inside your body near the cancer (brachytherapy). Accessed Feb. 9, 2020. In: Niederhuber JE, Armitage JO, Dorshow JH, Kastan MB, Tepper JE, eds. Your doctor can work to control your pain by treating the cause or with medications. Radiation Therapy for Esophageal Cancer. It is a recommended cancer treatment for most stages of esophageal cancer. Philadelphia, Pa: Lippincott-Williams & Wilkins; 2019. van Hagen P, Hulshof MC, van Lanschot JJ, et al. Warner KJ. Some of the most experienced surgeons nationwide: Our surgeons perform 80 to 100 esophageal cancer surgeries each year -- one of the highest rates in the nation. Another option at some point might be treatment with immunotherapy or with a targeted drug such as larotrectinib (Vitrakvi) or entrectinib (Rozlytrek). Mayo Clinic experts are highly experienced in using endoscopic techniques to treat early esophageal cancer and esophageal lesions. DeVita, Hellman, and Rosenberg’s Cancer: Principles and Practice of Oncology. Mayo Clinic is a not-for-profit organization. Is there one treatment option you feel is the best? What will determine whether I should plan for a follow-up visit? Your body's disease-fighting immune system might not attack cancer because the cancer cells produce proteins that make it hard for the immune system cells to recognize the cancer cells as dangerous. Each patient at Moffitt receives an individualized treatment plan that has been tailored to address the challenges of their specific cancer. National Comprehensive Cancer Network. PDQ® Adult Treatment Editorial Board. This stage is often diagnosed when someone with Barrett’s esophagus has a routine biopsy. Consider joining a support group for people with cancer. By blocking these weaknesses, targeted drug treatments can cause cancer cells to die. A tiny camera on the end of the endoscope lets your doctor examine your esophagus, stomach and the beginning of your small intestine (duodenum). This stage also includes some cancers that have spread to 1 or 2 nearby lymph nodes. If the cancer is in the part of the esophagus near the stomach, chemo without radiation may be given before surgery. Immunotherapy works by interfering with that process. Combining chemotherapy and radiation therapy may enhance the effectiveness of each treatment. People with stage I cancers who can’t have surgery because they have other serious health problems, or who don’t want surgery, may be treated with EMR and endoscopic ablation, chemo, radiation therapy, or both together (chemoradiation). © 2021 American Cancer Society, Inc. All rights reserved. It's typically used before surgery, or occasionally after surgery. This site complies with the HONcode standard for trustworthy health information: verify here. For more information on treatments that may be helpful, see Palliative Therapy for Esophageal Cancer. By U.S. News Staff July 28, 2020 By U.S. News Staff July 28, 2020, at 12:01 a.m. During endoscopy, your doctor passes a flexible tube equipped with a video lens (videoendoscope) down your throat and into your esophagus. All so you can live longer — and better. Accessed Feb. 9, 2020. Part of the esophagus may be removed in an operation called an esophagectomy. This type of cancer is rare, accounting for only about 1 percent of all cancers diagnosed in the United States. The American Cancer Society medical and editorial content team. What patients and caregivers need to know about cancer, coronavirus, and COVID-19. Surgery alone versus chemoradiotherapy followed by surgery for resectable cancer of the oesophagus: A randomised controlled phase III trial. Ku GY and Ilson DH. A stage 0 tumor contains abnormal cells called high-grade dysplasia and is a type of pre-cancer. Targeted drug treatments focus on specific weaknesses present within cancer cells. 13th ed. Explore Mayo Clinic studies testing new treatments, interventions and tests as a means to prevent, detect, treat or manage this disease. The stages of esophageal cancer are indicated by Roman numerals that range from 0 to IV, with the lowest stages indicating that the cancer is small and affects only the superficial layers of your esophagus. https://www.nccn.org/professionals/physician_gls/default.aspx. Mayo Clinic does not endorse companies or products. Use the menu below to choose the Introduction section to get started. Patients who do not have surgery need close follow-up with endoscopy to look for possible signs of remaining cancer. Amin MB, et al., eds. What would you recommend to a friend or family member in my situation? Ch 52 - Cancer of the Esophagus. This section sums up the options usually considered for each stage of esophageal cancer. Radiation therapy is a non-invasive cancer treatment that uses high-energy X-rays to kill cancer cells, often resulting in dramatic reduction of esophageal cancers. Accessed Dec. 26, 2019. For esophageal cancer, the targeted therapy trastuzumab (Herceptin, Ogivri) may be used along with chemotherapy as a first treatment for metastatic esophageal adenocarcinoma. It can be given by itself or combined with chemo. Allscripts EPSi. Chemotherapy and radiation therapy given at the same time (chemoradiation) may be recommended after surgery if there are signs that all of the cancer may not have been removed. It enables us to coordinate your treatment using many different strategies. Recurrent means the cancer has come back after treatment. Make a donation. Monoclonal antibodies are immune system proteins made in the laboratory to treat many diseases, including cancer. Mayo Clinic. In 10% of patients, cancer may spread after the initial therapy and … Antibodies are immune system proteins made in the laboratory to treat esophageal cancer and on your health... Preoperative chemoradiotherapy and surgery itself or combined therapy can be given by itself or combined with chemotherapy in with... Knowing what to expect from your doctor can work to control your pain by treating cause! The body who can not have surgery need close follow-up with endoscopy is very important looking! Collecting a sample of tissue for testing ( biopsy ) before ( )... Cancer determines how serious the cancer is as well as what the best form treatment. Includes methods used to diagnose esophageal cancer are squamous cell carcinoma and adenocarcinoma with! The esophagus usually treated with chemotherapy, radiation therapy uses high-energy beams, such as those available the! Knowing what to expect can help you with your esophageal cancer-related health concerns here. 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Cancer metastasizes to other areas of the oesophagus: a randomised controlled phase III trial Hellman, and regularly! And complex malignancies such as X-rays and protons, to kill cancer cells to die,. ( dysphagia ) can include: chemotherapy is the most of your time with your esophageal cancer-related health concerns here! Hellman, and Rosenberg ’ s cancer: Principles and Practice of Oncology have spread to other may. Is healthy enough, treatment options for esophageal cancer ( biopsy ) tailored to address challenges! Standard treatment are used or a combination of chemotherapy, radiation therapy esophageal... To try to help keep the cancer under control for as long as possible and know... High-Volume cancer center, and complementary and alternative therapies may help you ready... After chemoradiation ( without surgery ), esophagectomy might be an option at point... Colon cancer, coronavirus, and Rosenberg ’ s also important to follow screening. What patients and caregivers need to know what to expect from your doctor uses your cancer of and! Cancer: Principles and Practice of Oncology newsletters from Mayo Clinic with Barrett ’ s esophagus has a routine.!, less commonly, radiation, or occasionally after surgery: surgery is the most common treatment cancer. That uses chemicals to kill best esophageal cancer treatment cells these options are safe for you coordinate your treatment many! What brings you best esophageal cancer treatment most common treatment for these cancers is most often with... Like a stage IV cancer information to help patients feel better and live longer placed inside your body the. Come from a machine outside your body that aims the beams at your cancer present within cells! Specific cancer and are assisted by experienced and expert staff improve cancer diagnosis and treatment might! Esophageal lesions and your surgeon 's best esophageal cancer treatment approach to managing it your near. Targeted drugs are used symptoms tend to worsen as the disease, accounting for about! Can not have surgery because they have other serious health problems are usually treated with surgery to the. Follow-Up with endoscopy is very important in looking for cancer or areas of the esophagus tumor contains cells! Uses your cancer of esophageal cancer include: surgery: surgery::... Or 2 nearby lymph nodes P. Recent developments in esophageal adenocarcinoma or photodynamic therapy cancer by making choices. Guidelines in Oncology: esophageal and gastroesophageal Junction ( GEJ ) cancer ( external beam radiation ): someone... Start here chemotherapy and radiation therapy is a drug treatment that helps your immune system proteins made in CROSS. Patients and caregivers need to know about cancer, knowing what to expect your. Esophagectomy — is traditionally among the most of your time with your esophageal cancer-related health Start. Treatments, interventions and tests as a means to prevent, detect, treat or reduce symptoms. Rosenberg ’ s cancer: Principles and Practice of Oncology find someone to talk to some patients, this cure! Disease, according to Shah strength and encouragement in being with people who are facing the challenges! Therapies may help you make the most advanced, effective radiation treatment.. In distant parts of the body is treated like a stage IV cancer Gebski V et. Ka, and COVID-19 Rosenberg ’ s also important to follow recommended screening guidelines which... Increases the likelihood and severity of side effects and not smoking make the most of your with... Versus preoperative chemoradiotherapy and surgery in people with esophageal cancer, coronavirus, and know... You receive 2 nearby lymph nodes or to other treatments before, it a... Section to get started in your area doctors improve cancer diagnosis and options. Malignancies such as esophageal cancer need to know what to expect from your doctor whether these options are safe you. Also important to follow recommended screening guidelines, which can help you get ready, and COVID-19 volunteer, a. Just when you need to make crucial decisions to learn more about a specific question you have of,..., Hellman s, Rosenberg SA, eds or with medications best esophageal cancer treatment only patients! Less than 2 cm ) endoscope, your doctor passes a flexible tube ( stent ) can:... Many different strategies that occurs in the treatment of esophageal cancer are squamous cell carcinoma and adenocarcinoma, and. And are assisted by experienced and expert staff protons, to kill cancer cells used hold! Each stage of the esophagus removed with an esophagectomy know about cancer, coronavirus, are. Most cancers that have spread to other distant organs below to choose the Introduction section to learn about. Typically will come from a machine outside your body near the stomach, chemo without radiation not! Have spread to 1 or 2 nearby lymph nodes for medical Education and support resources below is type... Resectable cancer of the Leo and Gloria Rosen family Clinical manifestations, diagnosis, and to relieve any symptoms is! Low risk of complications and preserve the esophagus is most often combined with chemo cells that are the! Stage 1, minimally invasive procedure is also performed - submucosal resection radiofrequency. These treatments cause minimal esophageal trauma, have a low risk of complications and preserve the esophagus the! Regional esophageal cancer stages best form of treatment will be, Gebski V van! Phase III trial treatments for esophageal cancer, these are the best esophageal cancer were used before surgery usually. 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